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Application No. 10/701,244 
Paper Dated: October 1 8, 2007 
Attorney Docket No.: CV01679US (4686-050103) 



IN THE UNITED STATES PATENT AND TRADEMARK OFFICE 



Applicants: Jay S. Fine et al. 
Appl.No.: 10/701,244 



Group Art Unit: 1617 
Examiner: San Ming R. Hui 



Filed: 



November 4, 2003 



Case No.: CV01679US 



For: 



Methods and Therapeutic Combinations 
For the Treatment of Demyelination 



Confirmation No.: 6101 



SUPPLEMENTAL INFORMATION DISCLOSURE STATEMENT 



MAIL STOP AMENDMENT 
Commissioner for Patents 
P.O. Box 1450 
Alexandria, VA 22313-1450 



Sir: 



Applicants respectfully request that the following be considered and made of record, as well 
as the documents listed on the accompanying PTO Form SB/08A. 

(a) Pursuant to the duty of disclosure under 37 C.F.R. §1.56, it is requested that the 
documents listed on the accompanying Form SB/08A be considered and made of record in the above- 
identified patent application. Copy(ies) of these documents [X] are enclosed Q were filed in related 
U.S. Application No(s) filed , respectively. 

(b) No fee is believed to be due because: 

□ This Information Disclosure Statement is being submitted concurrently with 
the filing of the above-identified application; or 

n This Information Disclosure Statement is being submitted within three (3) 
months of the filing date of the above-identified application; or 

O This Information Disclosure Statement is being submitted concurrently with a 
Request for Continued Examination (RCE); or 

□ This Information Disclosure Statement is being submitted prior to the mailing 
of a first Office Action on the merits. 



(c) [X] This Information Disclosure Statement is being submitted before the mailing 
date of any final action, notice of allowance, or an action that otherwise 
closes prosecution; and: 



□ Each item of information contained in this Information Disclosure 
Statement was first cited in a communication from a foreign patent 
office in a counterpart foreign application not more than three months 
prior to the filing of this Information Disclosure Statement; or 

□ No item of information contained in this Information Disclosure 
Statement was cited in a communication from a foreign patent office 



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Application No. 10/701,244 
Paper Dated: October 1 8, 2007 
Attorney Docket No.: CV01679US (4686-050103) 

in a counterpart foreign application, and, to the knowledge of the 
undersigned after making reasonable inquiry, no item of information 
contained in this Information Disclosure Statement was known to any 
individual designated in § 1.56(c), more than three months prior to the 
filing of this Information Disclosure Statement; or 

□ The Commissioner is hereby authorized to charge the requisite fee 
listed on the attached Fee Transmittal Sheet. 



(d) D This Information Disclosure Statement is being submitted on or before the 
payment of the issue fee; and: 

L j Each item of information contained in this Information Disclosure 
Statement was first cited in a communication from a foreign patent 
office in a counterpart foreign application not more than three months 
prior to the filing of this Information Disclosure Statement; or 

O No item of information contained in this Information Disclosure 
Statement was cited in a communication from a foreign patent office 
in a counterpart foreign application, and, to the knowledge of the 
undersigned after making reasonable inquiry, no item of information 
contained in this Information Disclosure Statement was known to any 
individual designated in § 1.56(c), more than three months prior to the 
filing of this Information Disclosure Statement; and 

O The Commissioner is hereby authorized to charge the requisite fee 
listed on the attached Fee Transmittal Sheet. 



[X] The Commissioner is hereby authorized to charge any additional fees which may be required 
for this Information Disclosure Statement, or credit any overpayment to Deposit Account No. 
23-0650. 

Respectfully submitted, 



THE WEBB LAW FIRM 



Dated: October 18, 2007 

700 Koppers Building 
436 Seventh Avenue 
Pittsburgh, Pennsylvania 15219 
Telephone: 412-471-8815 
Facsimile: 412-471-4094 
E-mail: webblaw@webblaw.com 




-^*^Thomas C. Wolskf 
Reg. No. 55,739 



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